#27 Summary of Cell membrane

1 The basic structure of a membrane is a 7 nm thick phospholipid bilayer with protein molecules spanning the bilayer or within one or other layer. Phospholipids and some proteins move within the layers. Hence the structure is described as a fluid mosaic – the scattered protein molecules resemble pieces of a mosaic. 2 Phospholipid bilayers are a barrier to most watersoluble substances because the interior of the membrane is hydrophobic. 3 Cholesterol is needed for membrane fluidity and stability. 4 Some proteins are transport proteins, transporting molecules or ions across the membrane. They may be either channel proteins or carrier proteins. Channel proteins have a fixed shape; carrier proteins change shape. 5 Some proteins act as enzymes – for example, in the cell surface membranes of microvilli in the gut. 6 Glycolipids and glycoproteins form receptors – for example, for hormones or neurotransmitters. They also form antigens, which are cell recognition markers. 7 The cell surface mem...