#48 Summary of The mammalian heart
1 The human heart, like that of all mammals, has two atria and two ventricles. Blood enters the heart by the atria and leaves from the ventricles. A septum separates the right side of the heart, which contains deoxygenated blood, from the left side, which contains oxygenated blood. 2 Semilunar valves at the entrances to the blood vessels that leave the heart (aorta and pulmonary artery) prevent back flow of blood into the heart, and atrioventricular valves prevent backflow of blood from ventricles into the atria. 3 The heart is made of cardiac muscle and is myogenic (the muscle is self-stimulating). 4 The sinoatrial node (SAN) sets the pace of contraction for the muscle in the heart. Excitation waves spread from the SAN across the atria, causing their walls to contract. A non-conducting barrier prevents these excitation waves from spreading directly into the ventricles, thus delaying their contraction. Th e excitation wave travels to the ventricles via the atrioventric...